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Atomoxetine differs from traditional stimulant medications primarily in that it is not classified as a controlled substance. This distinction is significant because traditional stimulants, like methylphenidate and amphetamine-based medications, are typically categorized as controlled substances due to their potential for abuse and dependency. Atomoxetine, on the other hand, is approved for the treatment of attention-deficit hyperactivity disorder (ADHD) and is not associated with the same level of risk for abuse, which allows it to be prescribed more flexibly and monitored differently within healthcare settings.

In addition to this key difference, Atomoxetine has a different mechanism of action compared to traditional stimulants. It primarily functions as a selective norepinephrine reuptake inhibitor rather than enhancing dopamine transmission. Moreover, the onset of action of Atomoxetine tends to be slower compared to stimulants, which typically have a quicker onset of therapeutic effects. Lastly, Atomoxetine is approved for use in both children and adults, contradicting the suggestion that it is only for adult patients. Therefore, the correct choice regarding Atomoxetine's uniqueness in pharmacological classification is its status as a non-controlled substance.